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  -Given the structure of the anti-HIV drug azidothymidine (AZT) ,how do you think it blocks viral replication? A) It blocks RNA synthesis B) It inhibits host T cells from replicating C) It inhibits the assembly of new viruses in the cell D) It blocks DNA synthesis E) It prevents HIV from entering the cell -Given the structure of the anti-HIV drug azidothymidine (AZT) ,how do you think it blocks viral replication?


A) It blocks RNA synthesis
B) It inhibits host T cells from replicating
C) It inhibits the assembly of new viruses in the cell
D) It blocks DNA synthesis
E) It prevents HIV from entering the cell

F) B) and D)
G) C) and D)

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figure 15.4 figure 15.4   -SIV causes symptomless infections in monkeys and apes,yet causes AIDS-like disease in chimpanzees.HIV is closely related to SIV and causes AIDS in humans.Which of the following is the best explanation for these observations? A) Monkeys, apes, and chimpanzees are all genetically very similar B) The effects of viruses on different species is random C) Chimpanzees and humans have a more recent common ancestor D) SIV is most likely lytic in apes and monkeys E) SIV is most likely latent in chimpanzees -SIV causes symptomless infections in monkeys and apes,yet causes AIDS-like disease in chimpanzees.HIV is closely related to SIV and causes AIDS in humans.Which of the following is the best explanation for these observations?


A) Monkeys, apes, and chimpanzees are all genetically very similar
B) The effects of viruses on different species is random
C) Chimpanzees and humans have a more recent common ancestor
D) SIV is most likely lytic in apes and monkeys
E) SIV is most likely latent in chimpanzees

F) B) and C)
G) B) and E)

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Which of the following diseases is NOT caused by viruses?


A) The common cold and influenza
B) Smallpox and mononucleosis
C) Polio and rabies
D) Aids and warts
E) Diabetes

F) B) and C)
G) B) and D)

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How did the researchers first know that Marilyn the chimp may be infected with HIV?


A) Because she had HIV RNA in her blood
B) Because she had HIV DNA in her tissues
C) Because she had been used in HIV research
D) Because she had raised antibodies against HIV
E) Because she had symptoms of HIV infection, or AIDS

F) B) and D)
G) A) and B)

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The influenza virus contains an RNA genome.Every year the common flu vaccine is designed to protect against three different strains of the influenza virus.Why do scientists typically have to make a new vaccine every year?


A) Because our bodies develop resistance to the vaccine and it becomes less effective
B) Because the virus develops resistance to the vaccine
C) Because the virus can mutate into new strains
D) Because people change their habits each year and become susceptible to different strains of the virus
E) Because the common influenza virus can come from many species of animals including cats and dogs

F) A) and E)
G) All of the above

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The stage of viral replication in which viral components are put together to form new viruses is:


A) Release
B) Assembly
C) Attachment
D) Penetration
E) Synthesis

F) A) and E)
G) C) and E)

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Rhinovirus is an RNA virus that causes the common cold and sinus infections.The virus does not contain an envelope.Which of the following is true of a rhinovirus?


A) It does not contain protein or genetic material
B) It does not contain genetic material
C) It does not contain protein
D) It does not contain lipid or protein
E) It does not contain lipid

F) All of the above
G) B) and D)

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The treating of a viral infection by inoculating the host with a bacterial virus:


A) Is chemotherapy
B) Is phage therapy
C) Is radiation therapy
D) Is antibiotic therapy
E) None of these are correct

F) None of the above
G) B) and E)

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Many viruses are inhibited by antibiotics.

A) True
B) False

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The correct sequence of the stages of viral replication is:


A) Attachment - Synthesis - Penetration - Assembly - Release
B) Penetration - Attachment - Assembly - Synthesis - Release
C) Penetration - Attachment - Synthesis - Release - Assembly
D) Attachment - Penetration - Assembly - Synthesis - Release
E) Attachment - Penetration - Synthesis - Assembly - Release

F) D) and E)
G) B) and C)

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The stage of viral replication in which the new viruses leave the host cell is:


A) Release
B) Attachment
C) Penetration
D) Synthesis
E) Assembly

F) C) and D)
G) B) and E)

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Rhinovirus is an RNA virus that causes the common cold and sinus infections.The virus does not contain an envelope.What would you predict to be the primary route of transmission of rhinovirus?


A) Sexual contact
B) Blood
C) Aerosol
D) Insects
E) Parasites

F) A) and E)
G) B) and E)

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A vaccine against the influenza virus would result in production of antibodies against which of the following?


A) The protein coat
B) Viral RNA
C) Viral DNA
D) Proteins in the envelope
E) Lipids in the envelope

F) B) and D)
G) A) and C)

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figure 15.9 figure 15.9   -Based on figure 15.9,which of the following statements is most likely accurate? A) HIV arose more than once B) HIV groups M, N, and O will be more similar to each other than to SIV C) SIV only arose once D) The SIV strains will all have more sequence similarity with each other than with any of the HIV groups E) HIV and SIV are not genetically related -Based on figure 15.9,which of the following statements is most likely accurate?


A) HIV arose more than once
B) HIV groups M, N, and O will be more similar to each other than to SIV
C) SIV only arose once
D) The SIV strains will all have more sequence similarity with each other than with any of the HIV groups
E) HIV and SIV are not genetically related

F) A) and E)
G) A) and B)

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A capsid is:


A) A lipid coat of a virus
B) A viral DNA molecule
C) A protein coat of a virus
D) A viral RNA molecule
E) The area in the virus where its genetic information is located

F) B) and E)
G) None of the above

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Viral DNA inserted into a chromosome of the host is:


A) A carrier
B) A phage
C) A reservoir
D) A prophage
E) A lytic infection

F) C) and D)
G) B) and E)

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Viruses are not considered to be alive,yet they share this ability with living cells:


A) They can metabolize food
B) They can evolve
C) They can reproduce on their own
D) They can produce cell membranes
E) They can synthesize proteins

F) A) and C)
G) C) and D)

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The shape of a virus is determined by:


A) Its DNA
B) Its RNA
C) Its envelope
D) Its host
E) Its coat protein organization

F) C) and E)
G) C) and D)

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The enzyme that HIV uses to convert its RNA into DNA is:


A) Reverse transcriptase
B) DNA polymerase
C) RNA polymerase
D) RNA integrase
E) Transcriptase

F) A) and C)
G) A) and D)

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Poliomyelitis is an RNA virus that can invade the nervous system and cause paralysis within a matter of hours.Polio has been virtually eliminated world-wide by which of the following?


A) Antibiotics
B) Vaccination
C) Mosquito control
D) Quarantine
E) Improve water quality

F) A) and B)
G) D) and E)

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