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Place the steps of bacterial antigen processing and presentation in the correct order. 1. Lysosomal enzymes digest the bacterium into molecular bits. 2. The antigen - MHC complex is displayed on the cell surface. 3. The endocytic vesicle fuses with a lysosome. 4. A bacterium is engulfed by a phagocytic cell.


A) 4-3-1-2
B) 4-3-2-1
C) 3-4-2-1
D) 2-4-3-1

E) All of the above
F) None of the above

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If a person is incapable of making effector helper T cells, what will be the result?


A) Antibodies will not be produced.
B) Effector B cells will not be produced.
C) Memory B cells will not be produced.
D) Complement cascade will not occur.
E) Memory and effector B cells will not be produced.

F) B) and E)
G) A) and E)

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How are humans able to produce billions of unique B and T cell receptors?


A) Each time a pathogen is encountered, a new receptor is produced.
B) The two different genes that encode receptor proteins allow for many versions of receptors to be produced.
C) Random splicing of gene segments encoding receptor proteins allows for 2.5 billion potential combinations.
D) Antigen - presenting cells stimulate B and T cells to each produce billions of receptor molecules.
E) There are billions of B and T cells, each of which produces a single receptor on its cell surface.

F) B) and D)
G) None of the above

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Inflammation, complement proteins, and phagocytes are part of ____ immunity.


A) adaptive
B) innate
C) antibody-mediated
D) cell-mediated
E) surface barrier

F) B) and E)
G) B) and D)

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The goal of immunization is to ____.


A) limit the amount of time a person is ill with a disease
B) induce immunity to disease
C) enable infected individuals to recover from specific diseases
D) expose individuals to a disease
E) elicit an allergic response

F) None of the above
G) A) and C)

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The antibody-mediated immune response is most effective against ____.


A) cancer cells
B) viral infected cells
C) bacteria circulating in the blood
D) normal flora
E) self-cells

F) C) and E)
G) B) and D)

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Antibody molecules ____.


A) are secreted by B cells and T cells
B) stay attached to the B cell membrane as B cell receptors
C) inactivate complement proteins
D) prevent phagocytosis
E) can each bind to many different antigens

F) A) and B)
G) A) and C)

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Which of the following is a phagocyte that acts to alert the adaptive immune system of the presence of antigen in solid tissue?


A) macrophages
B) monocytes
C) neutrophils
D) dendritic cells
E) eosinophils

F) None of the above
G) A) and B)

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D

White blood cells that patrol interstitial fluid, phagocytize almost everything except uninjured body cells, and secrete cytokines to alert the adaptive immune system to threats are known as ____.


A) neutrophils
B) macrophages
C) T lymphocytes
D) dendritic cells
E) eosinophils

F) None of the above
G) A) and E)

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Once a stimulus for inflammation subsides, ____ produce compounds that suppress inflammation and promote healing.


A) neutrophils
B) macrophages
C) dendritic cells
D) T lymphocytes
E) monocytes

F) C) and D)
G) A) and B)

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T cells will begin to secrete cytokines when bound to a(n) ____.


A) MHC - antigen complex
B) receptor - antigen complex
C) antigen directly bound to the surface of a transport vesicle
D) antigen - antibody complex
E) bacterial pathogen

F) B) and E)
G) C) and D)

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A

____ patrol the blood and develop into phagocytic ____ that patrol tissues and interstitial fluid.


A) Macrophages; neutrophils
B) Neutrophils; macrophages
C) Dendritic cells; macrophages
D) Monocytes; macrophages
E) Monocytes; dendritic cells

F) A) and D)
G) A) and C)

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Acne results when bacterial secretions ____.


A) leak into internal tissues of follicles and cause inflammation
B) flow into open skin wounds
C) are swallowed and activate the innate immune response
D) mix with sweat and become more acidic.
E) are phagocytized by macrophages

F) A) and E)
G) B) and C)

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Antigen bearing particles in the blood travel to the ____, while those in solid tissues travel to the ____.


A) spleen; bone marrow
B) thymus; bone marrow
C) spleen; lymph nodes
D) lymph nodes; spleen
E) bone marrow; thymus

F) A) and E)
G) All of the above

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The cell-mediated immune response is most effective against ____.


A) cancer cells only
B) viral-infected cells only
C) bacteria circulating in the blood
D) both cancer cells and viral infected cells
E) normal flora

F) None of the above
G) A) and E)

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D

Complement proteins ____.


A) prevent pathogens from entering the interior environment of the body
B) bore channels in targeted cells, causing them to burst
C) inactivate other complement proteins
D) bind to pathogens making them a target for antibodies
E) destroy healthy body cells as well as invading microorganisms

F) C) and E)
G) B) and C)

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Since HIV attacks T cells, which type of immunity is affected in HIV-infected individuals?


A) innate
B) antibody-mediated
C) cell-mediated
D) inflammation
E) complement

F) C) and D)
G) A) and B)

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Smallpox ____.


A) was the target of the first vaccine
B) is spread by infected cattle
C) is only found in subtropical climates
D) was eradicated by 1850
E) is unrelated to cowpox

F) C) and E)
G) B) and E)

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Immunity ____.


A) is always adaptive
B) is an organism ' s ability to resist and combat infections
C) evolved after the emergence of multicellular organisms
D) is only found in mammals
E) is not specific for any given pathogen

F) D) and E)
G) A) and B)

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Place the following events of an inflammatory event in response to bacterial infection in proper order. 1. Activated complement binds to bacteria. 2) Capillary permeability increases. 3) Phagocytes engulf bacteria. 4) Mast cell receptors bind to bacterial antigens. 5) Signaling molecules cause arterioles to widen.


A) 4-5-2-1-3
B) 4-3-1-2-5
C) 5-2-1-4-3
D) 1-3-4-2-5
E) 5-2-4-1-3

F) A) and D)
G) A) and C)

Correct Answer

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